产品货号：
Z15431
中文名称：
EDC4抗体
英文名称：
Anti-EDC4 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-EDC4 Antibody |
| 指标别名 | Autoantigen Ge 1,Autoantigen RCD 8,EDC4,enhancer of mRNA decapping 4,Ge 1,HEDLS,RCD 8 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF,FCM,ELISA |
| 基因名称 | EDC4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human EDC4 recombinant protein (Position:K1082-L1388). |
| 实际分子量 | 152KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Enhancer of mRNA-decapping protein 4 is a protein that in humans is encoded by the EDC4 gene.Enhancer of mRNA decapping 4 (EDC4) was originally identified as the autoantigen Ge-1 from a Sj?gren's syndrome patient later diagnosed with primary biliary cirrhosis.EDC4 (also known as HEDLS) was later identified as an essential component of cytoplasmic P-bodies responsible for mRNA decapping and degradation.Identified EDC4 protein is found as a pair of isoforms generated by alternative splicing and contains several WD domains and a putative nuclear localization signal.EDC4 co-localizes with other P-body decapping proteins such as DCP1A,DCP2 and GW182.Experimental evidence suggests that EDC4 may be involved in miRNA-mediated translation repression. |
| Uniprot ID | Q6P2E9 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | enhancer of mRNA decapping 4 |
| 蛋白名全称 | Enhancer of mRNA-decapping protein 4 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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